The woman, who police will not name, was charged with two counts of careless driving causing death, and three counts of careless driving causing injury.
All charges relate to an incident near Poolburn on September 18, when shearer Stewart Hetaraka Smith (20), of Mataura, and wool handler Lavenia Setefano (19), of Gore, died at the scene of a single-vehicle crash on the Ida Valley-Omakau road.
The woman charged in relation to their deaths was driving the van they were travelling in, and will appear in the Alexandra District Court for the first time on April 8.
Central Otago's shearing community was in mourning after the crash, in which a Toyota Previa van being driven towards Oturehua rolled on a straight stretch of road about 6.15am and came to a stop upright in a nearby paddock.
All six occupants of the van, who worked for Alexandra-based shearing contractor Dion Morrell, were thrown from the vehicle.
Mr Morrell's 17- and 20-year old daughters, both of Alexandra, were two of three occupants flown by rescue helicopter to Dunedin Hospital with serious injuries.
On September 20 the Otago Daily Times, quoting Mr Morrell, reported his 20-year-old daughter Pagan Rimene was driving the van when it crashed.
Ms Rimene's uncle Dean Rimene, of Masterton, who was aged 40 at the time, was the front seat passenger in the vehicle when it crashed and was the third occupant flown to Dunedin by helicopter.
A 36-year-old Gisborne man was taken by ambulance to Dunstan Hospital at Clyde with moderate injuries.
On September 19 the Otago Daily Times reported Detective Sergeant Derek Shaw, of the Central Otago CIB, saying it was likely some, or all, of the occupants were not wearing seatbelts.
Fatigue and speed were reported as being likely factors in the crash.