Organised under the New Zealand Leadership Institute's Excelerator Future Leaders Programme, the seminar will be attended by up to eight pupils aged 16-19 from each of Central Otago's five secondary schools.
Southland schools have also been invited to send pupils.
The schools had been asked to nominate pupils showing potential to be leaders, co-ordinator Vic Coster said.
Ms Coster is a member of the Future Leaders Programme which comprises 24 people from throughout New Zealand.
Future Leaders Programme participants meet every three months and organise a trip to the home town of each member.
When Ms Coster's turn came up, she decided a youth leadership seminar in Cromwell would be a good idea.
"It's a great opportunity for our young people to have 24 leaders from different backgrounds and different places throughout New Zealand giving advice," she said.
The Cromwell seminar will be held at the Presbyterian Church, starting at 9.30am tomorrow.