The Lindis Pass (State Highway 8) has reopened after a crash closed the road for a time this afternoon.
NZ Transport Agency Waka Kotahi advised of the crash shortly after 1pm, saying "a serious incident has been reported to emergency services in this area".
A police spokesman said initial reports were that a vehicle had hit two pedestrians about 12.40pm.
In a follow-up statement police said two people were being taken to hospital with moderate injuries.
In an update about 2.20pm NZTA advised the highway had reopened, but said motorists could still expect delays.