It was men against boys as the powerhouse Dunedin pack dominated from the start and laid the platform for the win over Harbour at Watson Park.
Dunedin's powerful scrum was too big and strong and gained three tightheads, and lock Martin Swaffield was dominant in the lineout.
The best player in the Dunedin pack was flanker Gareth Evans, who made life miserable for Harbour with his strong running with the ball and his accurate tackling.
Evans, in partnership with No 8 Mark Atkins, made ground with driving rushes upfield that split open the defence.
The best Dunedin back was second five-eighth Jesse Toto with his powerful running.
He scored two first-half tries with the best coming after a 70m run that gave Dunedin a 26-10 lead at the break.
He was backed by powerful centre Tumua Ioane, who was able to crack open the defence to open up scoring opportunities, while fleet-footed fullback Liam Edwards added spark when he joined the line.
Dunedin took the game out of Harbour's reach when flanker Mitchell Zandstra scored after a 15m rolling maul that stretched the lead to 33-10.
The tentative Harbour backs gifted Dunedin its final try when winger Ashton Tuck intercepted and ran 40m.
Players to impress for Harbour were halfback Johnny Legg, flanker Angus Duckett, lock Sam Ready and winger Miwa Tadahino.
Dunedin 40 (Jesse Toto 2, Liam Edwards, Ashton Tuck, Mitchell Zandstra, Mark Atkins tries; Edwards con, 2 pen, Pera Gibbs con), Harbour 17 (George Folau, Wayne Gibson tries; Miwa Tadahino 2 con, pen). Halftime: 26-10.