Test-to-release possibility

Using a rapid antigen test (Rat) before ending self-isolation could be useful to avoid further transmission of Covid-19, some experts say.

At the traffic light Orange setting, you must self-isolate for seven days if you test positive.

But evidence published in the New England Journal of Medicine shows some cases can remain infectious after seven days.

Covid-19 Modelling Aotearoa co-lead Dr Emily Harvey said it varied from case to case.

"Broadly speaking, international evidence suggests that 10-25% of confirmed cases will still be infectious on day 8 (as measured by live virus that can be cultured in lab)."

"Obviously, this depends a lot on what gets counted as ‘day 0’."

She said because some people would still be infectious at the end of their isolation period, requiring a negative Rat result before being "released" from isolation could reduce onward infections.

A test-to-release scheme could potentially shorten the average isolation period.

"Some people will stop being infectious before day 7.

"Using test-to-release could allow some people to end their isolation early, and shorten the average isolation period, without increasing the risk of onward transmission," she said.

A Ministry of Health spokesman said the ministry acknowledged a small number of people would remain infectious for more than seven days after a positive Rat result.

"A positive Rat is a strong indicator of infectiousness, particularly at the beginning of the infectious period, but as time progresses and an individual recovers, a positive test is less likely to indicate infectiousness."

Eventually, a positive Rat was most likely to represent a false positive result.

Various combinations of testing and a mandatory period of isolation could be considered, but increasing the complexity of a strategy would usually result in poorer performance in practice.

"This is why the ministry does not recommend a Rat at day 7 and why it advises that anyone who has tested positive for Covid-19 should remain at home not only till day 7 after their positive Rat result (or from the onset of their symptoms, whichever is earlier), but also until 24 hours after their symptoms resolve."

simon.henderson@thestar.co.nz