Education officer Angela Verry said the Arrowtown museum was the only Otago venue hosting the travelling exhibition, a project brought out by the New Zealand Netherlands Foundation.
The public would enter the exhibition through a "secret annex", behind a book shelf.
Immediately, they would be taken into a room almost exactly the same size as one of those used by Anne and seven other people to hide in.
"The first room will be set up like Anne's bedroom. It's only a few feet out from the exact dimensions of the room she shared with Fritz Pfeffer [and others]."
The room would give people a better understanding of the close quarters and help to understand Anne's "observations of her room and her surroundings," Ms Verry said.
The main exhibition area would hold 11 panels, curated in Amsterdam, which had been exhibited around New Zealand since last year. The panels were divided in half with two time lines - one recording world events, the other the Frank family's lives.
"It's the story of one Jewish family and how they were affected by world events. It personalises every big event [in history], from the 1919 Treaty of Versailles through to the return of Otto Frank and the search to find his daughters."
Born on June 12, 1929, in Frankfurt am Main, Weimar Germany, Anne Frank was one of the best known and discussed Jewish victims of the Holocaust.
She was officially considered a German until 1941 when she lost her nationality, owing to the anti-Semitic policies of Nazi Germany.
The Frank family moved from Germany to Amsterdam in 1933, the year the Nazis gained control over Germany, and by the beginning of 1940 they were trapped in Amsterdam following the Nazi occupation of the Netherlands.
As persecutions of the Jewish population increased in July 1942, the family went into hiding in hidden rooms of Anne's father's office building.
After two years, the group was betrayed and transported to concentration camps - Anne and her sister, Margot, were transferred to the Bergen-Belsen concentration camp, where they both died of typhus in March 1945.
Otto Frank, the only survivor of the family, returned to Amsterdam after the war to find Anne's diary - given to her on her 13th birthday - had been saved. It chronicled her life from June 12, 1942, to August 1, 1944.
His efforts led to its publication in 1947, after which Anne gained posthumous international fame.
Ms Verry said in addition to the Anne Frank story, a DVD would be played to tell the stories of New Zealand Holocaust survivors with an interactive "Wailing Wall" to be erected where anyone who views the exhibition can text their reflections before leaving.
The exhibition opens to the public on Thursday, and she said already there had been great interest in the exhibition, with 2500 school pupils and a variety of community groups booked for tours.
The Lakes District Museum had also included a public lecture during the exhibition, in conjunction with the University of the Third Age.
On July 17 and 18 at the museum, Dr Susanne Ledanff, of Christchurch, would discuss the legacy of the Holocaust.
• "Anne Frank: A History for Today" opens at the Lakes District Museum on June 30 and will run until September 14. Dr Ledanff's lectures will be on July 17 at 2pm and July 18 at 10am. Places are limited, $5 entry fee.
