Hannah Lumsden, Saasha Bruce, Peyton Sweeney and Amanda Inkster (43), coxed by Jarrod Wellman (13), were first overall in the coxed quad category in a time of 1hr 15min.
"They had a storming race. They were great," said Inkster, who is club captain and coaches the juniors.
Georgina Galloway (16), coached by Dave Varney, was fourth in the women's single category of the Cromwell to Clyde race, in a time of 1hr 22min.
There were more than 60 crews in the race, held on October 26.
The women's team win was a welcome result after a long list of promising results for the teenagers at the Maadi Cup in April and this year's South Island Secondary School Championships.
The club backed up its success by recording a string of strong finishes at the Aoraki regatta at Twizel on November 8, when nine of 10 teams qualified for finals, including three novice teenage rowers.
Dozens of Wanaka residents - particularly girls and women - have taken up rowing since the club was founded last year.
There are now about 20 juniors and 20 senior members training on the lake at least three mornings a week and competing regularly.
Mrs Inkster (43) said the popularity of the sport among young women could be attributed to Georgina Galloway, whose third place in the under-17 single sculls B final at the Maadi Cup in April had inspired her friends and school-mates to take up the sport for fitness or competition.
The profile of New Zealand's Evers-Swindell rowing twins, Caroline and Georgina, who have won back-to-back Olympic gold medals, was probably also a factor, she said.
Mrs Inkster also coaches a group of between 8-12 masters women who have recently taken up the sport and train every Saturday morning from 10am.
Mt Aspiring College phys-ed teacher Rob Bruce is another coach and the club was keen to encourage more men and boys to join. Mrs Inkster rowed competitively at national level in the United Kingdom from about the age of 21 and later coached junior British rowers for 10 years.
She was on holiday in Wanaka and running along the beach in May 2007 when she came across across a small group of rowers and learned they were thinking about forming the club.
She and her husband Rob, an engineer, had selected Wanaka as their new home and were due to make the shift from Dartmouth, South Devon, last December, so she promised to get in touch when they returned.
Mrs Inkster kept her promise and has been involved with the club ever since.
"We were coming to Wanaka in particular and I was a bit sad because I thought there was no rowing club and I was going to have to get into multisport," she laughed.