Details of the hub were unveiled yesterday, showing car parks for the block would be gone.
All those spoken to yesterday had been involved in consultation with the Otago Regional Council as the bus hub plans were put together.
All planned to make submissions when a statutory process took place next year to get their concerns across.
Smiths Sports Shoes owner Robert Sansom said he had major concerns about the hub, and was ``totally against it''.
The business would lose all car parking on the street outside, and that was ``a big thing for us''.
In addition, buses would block the building, block signage and park with motors running.
There was also a health and safety issue about buses adding to movements on the busy road.
Mr Sansom said the footpath would be raised 30cm, meaning roadworks.
``There's nothing worse for a business than having months of road works.
``It's just deadly.''
A bus hub in Christchurch had been a disaster for businesses, with ``undesirables and gangs of kids'' hanging around, and reports of a loss of trade after 3pm when schools finished for the day, though the situation might be different in Dunedin, Mr Sansom said.
He had expressed concerns to the ORC, which had worked with businesses and made changes.
That included changing original plans to allow for loading zones for couriers.
But siting of bus seats was important.
``Who wants to have a bus seat outside the window where you display all your goods?''
Payless Party and Lifestyle owner Kristine Lunn said her business had ``major concerns'' about the hub.
``I actually believe that it will totally kill our businesses.''
Ms Lunn was also concerned about having bus seats outside shop windows, buses idling on the street, footpaths being raised and the effect of construction.
``It just seems to me they're going to do whatever they want to do, regardless of however we feel.''
The ORC had talked about removing awnings from the building.
The hub would put people out of work, she said.
``I just don't know why they can't put it somewhere else.''
Refined Rig clothing store director Peter Dean said he took the view the bus hub had to go somewhere, and that it was necessary.
``We don't really know whether it's going to have a negative effect on us or a positive effect or have no effect at all.''
There would be a loss of parking, which he was ``slightly concerned'' about, but perhaps more foot traffic outside his shop.
``The question is are the people who travel on buses in the socioeconomic group that would spend at shops like ours?
``I don't know.''
If Great King St was the best place for the hub, he was happy with that.
``We probably need to look into it a bit more and put a submission in.''
Dunedin Community House manager Alan Shanks said his organisation wanted to view the plans ``a little bit more closely'' at the Civic Centre today, before making a comment.
``We will certainly be making some feedback, that's for sure.''
The noise and look of the hub were issues that would need to be considered.
The Farmers department store in the street has been involved in consultation, and has concerns, but an Auckland-based employee involved did not return a call yesterday.
An ORC spokesman said consultation with those neighbouring the site would be ongoing.
