Only one serious crash, near Tarras on Thursday night, had been reported by last night.
"Generally the public have been very well behaved," acting road policing manager Senior Sergeant Steve Larking said.
The relatively smooth weekend was mirrored throughout New Zealand, with a record fatality-free Easter.
Five people were killed on the roads last Easter.
The record for the lowest Easter holiday toll is three fatalities, recorded in 1998, 2002 and 2003.
Acting national road policing manager Rob Morgan last night urged caution in the remaining hours of the road-toll period.
"We're still not counting our chickens though - we've still got a way to go."
Mr Morgan said it would be remarkable if the lowest Easter road toll eventuated.
"When we were back in the early '90s and '80s, we were killing 15, 19, 16... we had 12 killed in 2010."
By 1pm yesterday, police had attended 455 crashes since the Easter road toll period began at 4pm on Thursday, compared with 517 by the same time last year.
Sen Sgt Larking said there had been a visible police presence in Central Otago areas popular with holiday-makers. Extra staff from rural drink-driving, alcohol, highway patrol and traffic groups from around the police district had targeted roads in thase areas.
Tickets had been issued for the usual infringements, including speeding, failing to keep left and drink-driving, as well as to some drivers who were pulled over for driving too slowly.
Snr Sgt Larking said several staff had been tasked with spotting drivers holding up traffic, and instructing waiting patrols to pull over those vehicles, so officers could have a word with drivers.
Several tickets were issued, but the exercise was mainly about educating drivers, he said.
The highest speed checked was a motorist travelling at 151kmh, and the worst drink-driver a man checked after the Clyde Wine and Food Festival who was more than twice the legal breath alcohol limit.
"We were pleased we got him off the road, because he could have been a fatal waiting to happen."
He said traffic to Central Otago had been heavy at the start of the holiday, but was not as heavy leaving yesterday, as people had to resume work on different days.
Dunedin-Clutha area road policing manager Senior Sergeant Phil McDouall said police had also been pleased with driver behaviour in Dunedin over the holiday.
While it had been relatively quiet in the city, drivers had been following the rules and driving respectfully over the long weekend.
