A Fire and Emergency New Zealand spokesman said three people had managed to get out of the vehicle without assistance.
Crews from Weston, Oamaru and Kakanui assisted the ambulance at the scene this morning at about 10.10am.
Hato Hone St John said a first response unit and a helicopter from Dunedin responded to the incident on private farmland in Waianakarua Rd in Kakanui.
One person was taken to Oamaru Hospital by ambulance and another was airlifted by helicopter to Dunedin Hospital in a moderate condition.
WorkSafe was notified and was making initial inquiries however a spokesman said it was not an investigation at this stage.