The Toll truck and trailer, travelling north to Tarras on State Highway 8, overturned about 7.30am after the driver failed to take a minor bend, Central Otago sub-area supervisor Senior Sergeant Clint Wright said.
The driver, the only occupant of the truck, was taken to hospital with minor injuries. The road was closed following the accident until 2.21pm.
Police inquiries into the incident were continuing, Snr Sgt Wright said.
A Toll spokeswoman said the company would conduct "a full investigation" into the cause of the accident.
"Toll takes safety extremely seriously and the welfare of our people and the community is our highest priority. We are supporting our driver, and co-operating with authorities and emergency services at the scene."
A WorkSafe spokesman said WorkSafe had not been notified of the incident.
