Aaron Smith
Aaron Smith, Ben Smith and Malakai Fekitoa have all been left out of the team to play in Canberra.
With seven forwards also out injured there are six changes to the side to face the Australian conference leaders.
The Brumbies are due to name their team later today.
Highlanders: Trent Renata, Waisake Naholo, Richard Buckman, Shaun Treeby, Patrick Osborne, Lima Sopoaga, Fumiaki Tanaka, Nasi Manu (captain), James Lentjes, Elliot Dixon, Joe Wheeler, Tom Franklin, Pingi Tala'apitaga, Liam Coltman, Kane Hames. Reserves: Ash Dixon, Brendon Edmonds, Josh Hohneck, Joe Latta, Gareth Evans, Dan Pryor, Josh Renton, Jason Emery
