The twin-engine King Air plane, with 11 people onboard, went down on Friday evening (local time) soon after takeoff from Dillingham Airfield and there were no survivors, the Hawaii Department of Transportation (HDOT) said.
The fire service said the aircraft was engulfed in flames when fire crews arrived. "We are still gathering information as to the intent of the flight and what they were doing," Honolulu Fire Department Chief Manuel Neves told a news conference.
CNN said the plane was on a skydiving excursion and the Federal Aviation Administration would investigate.
The HDOT said Federal inspectors are continuing to investigate the cause of the crash.
Dillingham is a joint-use airfield operated by the HDOT under a 25-year lease from the US army, according to its website.