The former pupils, who left Otago Boys' in 2009, returned yesterday to inspire their old schoolmates.
Rector Clive Rennie said the former pupils were part of a successful year academically.
Eight of the 10 attained scholarships, and the group included former head boy Nick Dunbar, dux Sehan De Silva and joint proxime accessit Andrew Sise and Kamil Patel.
The others are: Gunveen Singh, Jamie Sinclair, Juno Pyun, Sam Haslam, Fraser Prendergast and Daniel Gold.
The school had never had so many former pupils accepted into medical school in one intake, Mr Rennie said.
The most previously was "five or six" pupils from one year.
Mr Rennie said Mr Dunbar spoke to the school assembly, encouraging pupils to aim high and work hard to achieve their goals.
It was especially useful for older pupils, many of whom remembered the former pupils well, as it was a good reminder for them to "up the ante" academically.
All aged 19, the university students said they studied together during their senior school years and kept up the contact and spirit of teamwork throughout their first year at Otago, where they studied health sciences, a prerequisite to entering medical school.
Mr Sise said the group had a healthy spirit of competition, which kept them on their toes academically.
Except for Mr Patel, whose parents moved back to South Africa meaning he spent a year living in a hall of residence (Arana), the others lived at home during their first year of university.
