Low has been battling diffuse gastric cancer since late last year.
This included a six-hour operation to remove his entire stomach, followed by a significant amount of weight loss. He had planned to hit the road again in June with the NZ Highwaymen, but has decided the rigours of touring — rehearsals, sound checks, travel, and the performances themselves — would be too demanding.
The tour is going around New Zealand and includes performances at Wanaka on June 29, Alexandra the next day, Mosgiel on July 2 and Waimate on July 4.
Low (81) will be replaced by Frankie Stevens (74).
"Frankie is an entertainment veteran and I have full faith in his ability to deliver an incredible show. So much work has gone into planning this tour, and although I won't be there physically, I'll be cheering them on every step of the way," Low said.
"Frankie is a great showman, and I want the fans to support him and the rest of the band."
The other three musicians in the NZ Highwaymen are Brendan Dugan, Gray Bartlett and Dennis Marsh.