A driver emerged relatively unscathed from a collision which wrote off their car when it collided with a truck near Mosgiel.
Senior Sergeant Anthony Bond, of Dunedin, said officers were called to State Highway 1 about 9.15pm on Tuesday.
A driver lost control and hit a truck and trailer, he said.
The car was a write-off and the truck was extensively damaged, Snr Sgt Bond said.
A St John spokeswoman said one ambulance attended and treated two patients at the scene for minor injuries.