Playing in the Deutsche Bank Championship, Lee has carded a one-under par 70 to be in a tie for 26th after the first round of the tournament.
Lee started off strongly by birdieing his first hole, before bogeying the par-five second.
He picked up another stroke on the ninth to head to the turn at one-under before mixing in another bogey and birdie to card the opening round of 70.
Zimbabwe's Brendon De Jonge leads the tournament at six-under par, two strokes ahead of a chasing pack of nine players which includes Luke Donald, Ian Poulter, Henrik Stenson and Rickie Fowler.
Jason Day is at three-under after winning back-to-back events, Rory McIllroy is at one-under while Jordan Spieth has had another poor round, shooting a four-over 75.
The event is the second of the four FedEx Cup playoff tournaments, with US$8,250,000 on the line.
The top 70 golfers on the year-long FedEx leaderboard will progress to next week's BMW Championship, with Lee confirmed of a spot as a result of currently sitting in 10th on the season-long ladder.
Lee is also looking to hold onto the 10th and final automatic berth on the international team for the President's Cup, with the top 10 international players in the world rankings at the conclusion of this week receiving automatic selection.
Lee is currently ranked 53rd in the world, with Australian Steven Bowditch just one place behind in 54th. However, Bowditch opened with a five-over par 76, making his chances of passing Lee slim, while Lee is also likely to receive a captain's pick even if he is surpassed this weekend.