Mrs Bremner's last day is in March next year.
Her husband, Graeme, a forensic scientist, has been appointed associate professor at a university in Palapye, Botswana.
Mrs Bremner (64) said she was not sure what she would do, but there were opportunities in a developing economy.
She is toying with the idea of setting up a wedding planning business.
Their 20-year-old son is considering moving there to set up a nocturnal wildlife tour business.
Botswana was a stable and well-organised country, and New Zealand could learn from its infrastructure planning. Palapye had been well planned to cater for an expanding population, she said.
``It doesn't feel like an unsafe place to be.
``Of all of the African countries, it's probably the easiest place to go.''
Presbyterian Support Otago has an annual turnover of $32million a year, and about 740 staff working in aged residential care, social work, and other programmes.
Mrs Bremner said she had always thought it would be a good thing to leave Dunedin when she retired from PSO.
``This has been a big part of my life. It's very difficult to leave it behind.
``Looking on at close quarters here in Dunedin would not have been an easy thing for me to do.''
Eventually, the couple would return to New Zealand for their retirement.