A driver emerged relatively unscathed but their car was written off after it collided with a truck near Mosgiel.
Senior Sergeant Anthony Bond, of Dunedin, said officers were called to the East Taieri-Allanton Rd (State Highway 1) about 9.15pm yesterday.
A car had lost control and hit a truck and trailer.
The car was a write-off and the truck was extensively damaged, Snr Sgt Bond said.
A Hato Hone St John spokeswoman said one ambulance attended and treated two patients at the scene for minor injuries.
